Resistance to Early-Life Stress in Mice: Effects of Genetic Background and Stress Duration

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Resistance to Early-Life Stress in Mice: Effects of Genetic Background and Stress Duration

Early-life stress can induce marked behavioral and physiological impairments in adulthood including cognitive deficits, depression, anxiety, and gastrointestinal dysfunction. Although robust rat models of early-life stress exist there are few established effective paradigms in the mouse. Genetic background and protocol parameters used are two critical variables in such model development. Thus w...

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Oxidative stress has recently been suggested to play an important role in life-history evolution, but little is known about natural variation and heritability of this physiological trait. Here, we explore phenotypic variation in resistance to oxidative stress of cross-fostered yellow-legged gull (Larus cachinnans) chicks. Resistance to oxidative stress was not related to plasma antioxidants at ...

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ژورنال

عنوان ژورنال: Frontiers in Behavioral Neuroscience

سال: 2011

ISSN: 1662-5153

DOI: 10.3389/fnbeh.2011.00013